This Slashdot article really got me thinking. 1.4 Terabytes for $2,000. Then you can start adding drives at will to increase your storage without incurring any penalties.
Get a CoolerMaster Stacker enclosure like this one (just the hardware not the software) that can hold up to 12 SATA drives. Install OpenSolaris and create ZFS pools with RAID-Z for redundancy. Export some pools with Samba for use as a NAS. Export some pools with iSCSI for use as a SAN. Run it over Gigabit Ethernet. Fast, secure, reliable, easy to administer, and cheap. Usable from Windows, Mac, and Linux. As a bonus ZFS let’s me create daily or hourly snapshots at almost no cost in disk space or time.